The proteasome is a structural complex of many proteins that degrades substrates marked by covalent linkage to ubiquitin.Many years of research has shown a role for ubiquitin-proteasome-mediated proteolysis in synaptic plasticity and memory mainly in degrading synaptic, cytoplasmic and nuclear proteins.Recent work indicates that the proteasome has
Serving Platters Abstract Background Gallstone disease poses a global threat to human health and is strongly linked to environmental factors.However, there is currently no data on the presence of rare earth elements (REEs) in human gallstones.This paper investigates the concentration and distribution of REEs in gallstones for the first time, aiming
Pneumocephalus is defined as the presence of air in the intracranial cavity.In most cases, its evolution is asymptomatic and benign.Pneumocephalus post-surgery is a frequent complication of cranial surgery.We herein report delayed tension pneumocephalus after craniotomy for pituitary macroadenoma.A 73-year-old man with recurrent pituitary macroaden
The ability to recover purposeful movement soon after debilitating neuromuscular injury is essential to animal survival.Various neural and mechanical mechanisms exist to preserve whole-limb kinematics despite exhibiting long-term deficits of individual joints following peripheral nerve injury.However, it is unclear whether functionally relevant who